Scientific Overview

Transcranial Magnetic Stimulation

Transcranial Magnetic Stimulation (TMS) is a non-invasive technique to stimulate the cortical regions of the brain when applied with proper parameters. TMS has been used in medicine for over three decades.

TMS utilizes electromagnetic induction to generate weak electric currents. This causes enhancement of the activity in targeted parts of the brain. Repetitive TMS, as used in neuroAD Therapy System, produces changes in synaptic efficacy. These changes enhance LTP processes, which in turn promote learning, and have a long-lasting effect [1].

TMS systems are currently CE-marked and FDA-cleared for the treatment of clinical depression (MDD), with widely accepted safety guidelines already in place. TMS is also undergoing clinical studies for use in various other indications. These include stroke, Parkinson’s Disease, Tinnitus and more. neuroAD is the only system to employ TMS, combined with targeted Cognitive Training, and is CE-marked for treating mild to moderate Alzheimer’s Disease.

[1] Fitzgerald PB; Fountain S; Daskalakis J (December 2006). “A comprehensive review of the effects of rTMS on motor cortical excitability and inhibition”. Clinical Neurophysiology 117 (12): 2584–96.

neuroAD is an investigational device currently not commercially available in the United States.
neuroAD is CE-cleared and commercially available for the treatment of mild to moderate Alzheimer’s Disease in Europe.